The Research...
Natural therapies in the medical literature

We list below a number of studies showing the benefit of certain naturopathic interventions with respect to various disease conditions. These by no means represent all studies, only a sampling of the extant medical literature. Whenever feasible, and for the sake of brevity, we have limited our citations to a maximum of two per therapy and two therapies per disease condition. The amount of research supporting natural therapies is indeed extensive, well over one hundred times the number of medical journal articles cited herein. In choosing this relatively very small number of articles to cite here, we have opted for both a breadth of coverage of the many diseases having successful natural treatments, as well as a preference for the meta-analyses and larger studies over smaller studies and case studies.

The reader should never consider the following information as a substitute for consultation with a naturopathic physician or another qualified health professional. In fact, from reading the list below, one could not determine appropriate dosing or follow-up for any of the remedies described. Also, in some situations the below treatments may not be appropriate under a given set of circumstances or conditions. A basic tennant of Naturopathic treastment is to treat the whole person. Therefore, your naturopathic physician will work with you to determine which treatments are most appropriate given your condition and circumstances.

Addiction

Acupuncture:

G. ter Riet, et al. "A meta-analysis of studies into the effect of acupuncture on addiction," British Journal of General Practice 1990; 40: 379-382.

Alzheimer's Disease

L-Acetyl Carnitine:

B. Bowman, "Acetyl-L-Carnitine and Alzheimer's Disease," Nutrition Reviews 1992; 50: 142-44.

M. Calvani, "Action of Acetyl-L-Carnitine In Neurodegeneration and Alzheimer's Disease," Ann NY Academy of Science 1993; 663: 483-86.

Ginkgo Biloba:

F. V. de Feudis, ed. "Ginkgo Biloba Extract (EGB 761)," Pharmacological Activities and Clinical Implications, (Paris: Elsevier, 1991).

J. Kleijnen and P. Knipschild, "Ginkgo Biloba," Lancet 1992; 340: 1136-39.

Anemia, Pernicious

Vitamin B-12 (Cobalamin):

F. A. Lederly, "Oral Cobalamin for Pernicious Anemia: medicine's best-kept secret,"JAMA 1991; 265: 94-95.

E. H. Reisner et al., "Oral treatment of pernicious anemia with Vitamin B-12 without intrinsic factor," New England Journal of Medicine 1955; 253: 205-06.

Angina

L-Carnitine:

T. Kamikawa, et al. "Effects of L-Carnitine on exercise tolerance in patients with stable angina pectoris," Japanese Heart J 1984; 25: 587-97.

L. Cacciatore, et al. "The therapeutic effect of L-Carnitine in patients with exercise-induced stable angina: a controlled study," Drugs Exptl Clin Res 1991; 17: 225-335.

Coenzyme Q-10:

K. Folkers and Y. Yamamura, eds. Biomedical and Clinical Aspects of Coenzyme Q-10. Vols. 1-4 (Amsterdam: Elsevier Science Publishers, Vol. 1: 1977, Vol. 2: 1980, Vol. 3: 1982., Vol. 4: 1984).

T. Kamikawa et al. "Effects of Co-Enzyme Q-10 on exercise tolerance in chronic stable angina pectoris," American Journal Cardiol 1985; 56: 247.

Anxiety/Panic Attacks

Omega-3 Essential Fatty Acids:

D. Rudin. "The Major Psychoses and Neuroses as Omega-3 Essential Fatty Acid Deficiency Syndrome: Substrate Pellagra." Biol Psychiatry 1981; 16: 837-50.

Kava root:

Y. Singh. "Kava: an overview," J Ethnopharmacol 1992; 37: 13-45.

E. Kinzler, J Kromer et al. "Clinical efficacy of a kava extract in patients with anxiety syndrome: double-blind placebo controlled study over 4 weeks," Arzneim Forsch 1991; 41: 584-88.

Asthma

Fish oil:

L. Hedge, et al. "Consumption of oily fish and childhood asthma risk," MJA 1996; 164: 137-40.

J. Dry, D. Vincent. "Effect of a fish oil diet on asthma: results of a 1-year double-blind study," Int Arch Allergy Apply Immunol 1991; 95: 156-57.

Vitamin B-6 (Pyridoxine):

P. Collip, S. Goldzeir, et al. "Pyridoxine treatment of childhood asthma," Ann Allergy 1975; 35: 93-7.

S. Sur, et al. "Double-blind trial of pyridoxine (Vit. B-6) in the treatment of steroid-dependent asthma." Ann Allergy 1993; 70: 147-52.

Homeopathy:

J. H. Campbell, et al. "Is homeopathy a placebo response? A controlled trial of homeopathic immunotherapy in atopic asthma," Am. Rev. Resp. Dis. 1990; 141: A24.

K. Linde, et al. "Homeopathy for chronic asthma," Cochrane. Database. Syst. Rev. 2000; CD000353.

Attention Deficit Disorders

Diet, general:

M. Lipton, J. Mayo. "Diet and hyperkinesis: an update," J Am Diet Assoc, 1983; 83: 132-34.

R. Prinz, et al. "Dietary correlates of hyperactive behavior in children," J Consult Clin Psych 1980; 48: 760-69.

Removing lead:

O. David, et al. "Lead and hyperactivity," Lancet 2(1972) 900-03.

R. W. Tuthill, "Hair lead levels related to children's classroom attention deficit behavior," Arch Environ Health 1996; 51: 214-20.

Bronchitis

Homeopathy:

F. Balsano, et al. "Effetto di un composto glicoproteico estratto da Klebsiella pneumoniae sul decorso clinico di infezioni acute delle vie aeree in pazienti affetti da bronchite cronica," Rec. Prog. Med. 1988; 79: 73.

Cancer

Homeopathy:

P. Drossou, et al. "Homoeopathic treatment of leukaemias," Homeopathy International 1990 May: 12.

Cervical Dysplasia

Folic acid:

W. Van Niekerk, "Cervical cytological abnormalities caused by folic acid deficiency," Acta Cytol 1966; 10: 67-73.

N. Whitehead, et al. "Megaloblastic changes in the cervical epithelium association with oral contraceptive therapy and reversal with folic acid," JAMA 1973; 226: 1421-4.

Cholesterol

Pantothenic Acid (Vitamin B-5):

A. Gaddi, et al. "Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia," Atheroscl 1984; 50: 73-83.

C. Donati, et al. "Pantethine, diabetes mellitus and atherosclerosis: clinical study of 1045 patients," Clin Ter 1989; 128(6): 411-22.

Garlic:

M. Steiner, et al. "A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids," American Journal of Clinical Nutrition 1996; 64: 866-70.

S. Warshafsky, et al. "Effect of garlic on total serum cholesterol," Ann Intern Med 1993; 119: 599-605.

Chronic Fatigue Syndome

Magnesium:

I. M. Cox, et al. "Red blood cell magnesium and chronic fatigue syndrome," Lancet 1991; 337: 757-60.

Common Cold

Vitamin C:

L. Pauling, "Vitamin C and the common cold" (San Francisco: Freeman, 1970).

H. Hemila, et al. "Vitamin C and the common cold: A retrospective analysis of Chalmers' review," J Am Coll Nutr 1995; 14: 116-23.

Echinacea:

D. Melchart, et al. "Immunomodulation with Echinacea: A systemic review of controlled clinical trials," Phytomed 1994; 1: 245-54.

D. Schoneberger, "The influence of immune-stimulating effects of pressed juice from Echinacea purpurea on the course and severity of colds: Results of a double-blind study," Forum Immunologie 1992; 8: 2-12.

Traditional Chinese Medicine:

C. Liu, et al. "Chinese herbal medicines in the treatment of acute respiratory infections: a review of randomized and controlled clinical trials," Medical Journal of Australia 1998: 579-582.

Depression

Folic acid:

E. Reynolds, et al. "Folate deficiency in depressive illness," Br J Psychiat 1970; 117: 287-92.

S. L. Kivela, et al. "Depression in the aged: Relation to folate and vitamins C and B-12," Biol Psychiatry 1989; 26: 209-13.

St. John's Wort (Hypericum):

H. Sommer, et al. "Placebo-controlled double-blind study examining the effectiveness of a hypericum preparation in 105 mildly depressed patients," J GeriatrPsychiatry Neurol 1994; 7 (Suppl 1): S9-11.

G. Harrer, et al. "Effectiveness and tolerance of the hypericum extract LI 160 compared to Maprotiline: A multicenter double-blind study," J Geriatr Psychiatry Neurol 1994; 7 (Suppl 1): S24-8.

E. U. Vorbach, et al. "Effectiveness and tolerance of the hpyericum extract LI 160 in comparison with imipramine: randomized double-blind study with 135 outpatients," J Geriatr Psychiatry Neurol 1994; 7 (Suppl. 1): S19-23.

Detoxification

Homeopathy:

P. Fisher, et al. "The influence of the homoeopathic remedy Plumbum metallicum on the excretion kinetics of lead in rats," Human Toxicology 1987; 6: 321.

Diabetes

Chromium:

R. Anderson, et al. "Beneficial effect of chromium for people with type II diabetes," Diabetes 1996; 45 (Suppl. 2): 124A/454.

R. Levine, et al. "Effect of oral chromium supplementation on the glucose tolerance of elderly human subjects," Metabolism 1968; 17: 114-25.

Fish:

L. Cobias, et al. "Lipid, lipoprotein, and hemostatic effects of fish vs fish oil w-3 fatty acids in mildly hyperlipidemic males," Am J Clin Nutr 1991; 53: 1210-16.

E. J. M. Feskens, et al. "Inverse association between fish intake and risk of glucose intolerance in normoglycemic elderly men and woman, Diabetes Care 1991; 14: 935-41.

Homeopathy:

A. Cier, et al. "Sur le traitement du diabete expérimental par des dilutions infinitésimals d'alloxane," Ann. Hom. Fr. 1966; 8: 137.

Diarrhea

Homeopathy:

J. Jacobs, et al. "Treatment of acute childhood diarrhea with homeopathic medicine: a randomized clinical trial in Nicaragua," Pediatrics 1994; 93: 719.

J. Jacobs, et al. "Homeopathic treatment of acute childhood diarrhea: results from a clinical trial in Nepal," J. Alt. Compl. Med. 2000; 6: 131.

Ear Infections

Homeopathy:

H. Harrison, et al. "A randomized comparison of homoeopathic and standard care for the treatment of glue ear in children," Complement. Ther. Med. 1999; 7: 132.

J. Jacobs, et al. "Homeopathic treatment of acute otitis media in children: a preliminary randomized placebo-controlled trial," Pediatr. Infect. Dis. J. 2001; 20: 177.

Eczema

Evening Primrose Oil:

J. C. M. Stewart, et al. "Treatment of severe and moderately severe atopic dermatitis with evening primrose oil (epogam): a multicenter study," J Nutr Med 1991; 2: 9-15.

C. A. Hederos, et al. "Epogam evening primrose oil treatment in atopic dermatitis and asthma," Arch Dis Child 1996; 75(6): 494-7.

Traditional Chinese Medicine:

D. J. Atherton, et al. "Treatment of atopic eczema with traditional Chinese medicinal plants," Pediatr Dermatol 1992; 9(4): 373-5.

M. P. Sheehan, et al. "Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis," Lancet 1992; 340: 13-7.

Fibrocystic Breast Changes

Caffeine:

C. A. Boyle, et al. "Caffeine consumption and fibrocystic breast disease: a case-control epidemiologic study," JNCI 1984; 72: 1015-9.

V. L. Ernster, et al. "Effects on caffeine-free diet on benign breast disease: a random trial," Surgery 1982; 91: 263-7.

Fibromyalgia

5HT-1:

I. Caruso, et al. "Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome," J Int Med Res 1990; 18: 201-9. P. S. Puttini, et al. "Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study," J Int Med Res 1992; 20: 182-9.

Magnesium:

T. J. Romano, et al. "Magnesium deficiency in fibromyalgia syndrome," J Nutr Med 1994; 165-7.

I. M. Cox, et al. "Red blood cell magnesium and chronic fatigue syndrome," Lancet 1991; 337: 757-60.

Acupuncture:

B.M. Berman, et al. "Is acupuncture effective in the treatment of fibromyalgia?" Journal of Family Practice 1999; 48: 213-218.

Homeopathy:

P. Fisher, et al. "Effect of homoeopathic treatment on fibrositis (primary fibromyalgia)," Brit. Med. J. 1989; 299: 365.

Flu

Homeopathy:

G. Lewith, et al. "Controlled study of a homoeopathic dilution of influenza vaccine on antibody titres in man," Comp. Med. Res. 1989; 3: 22.

Gallstones

Food allergy:

J. C. Breneman, "Allergy elimination diet as the most effective gallbladder diet," Ann All 1968; 26: 83-7.

H. Necheles, et al. "Allergy of the gallbladder," Am J Dig Dis 1949; 7: 238-41.

Lecithin:

S. A. Tuzhilin, et al. "The treatment of patients with gallstones by lecithin," Am J Gastroenterol 1976; 65: 231.

I. Hanin, et al. "Lecithin: technological, biological and therapeutic aspects," (New York: Plenum Press 1987).

Glaucoma

Vitamin C:

S. Fishbein, et al. "The pressure lowering effect of ascorbic acid," Annal Opthamol 1972; 4; 487-91.

E. Linner, "The pressure lowering effect of ascorbic acid in ocular hypertension," Acta Opthamol 1969; 47: 685-9.

Fish oil:

R. McGuire, "Fish oil lowers ocular pressure," Medical Tribune 1991; August 19: 25.

Gout

Flavonoids:

T. Yoshimoto, et al. "Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase," Biochem Biophys Res Comm 1983; 116: 612-8.

L. W. Blau, "Cherry diet control for gout and arthritis," Texas Rep Biol Med 1950; 8: 309-11.

Hay Fever

Nettles:

P. Mittman. "Randomized double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis," Planta Medica. 1990; 56: 44-47.

Homeopathy:

M. Wiesenauer, et al. "Double-blind trial comparing the effectiveness of the homeopathic preparation Galphimia potentisation D6, Galphimia dilution 10-6 and placebo on pollinosis," Arzneimittelforschung Drug Res. 1985; 35: 1745.

D. Taylor Reilly, et al. "Is homeopathy a placebo response? Controlled trial of homoeopathic potency, with pollen in hayfever as a model," Lancet 1986; 2: 881.

Headache and Migraine

Food allergy:

L. E. Mansfield, et al. "Food allergy and adult migraine: double-blind and mediator confirmation of an allergic etiology," Ann Allergy 1985; 55: 126-9.

J. Monro, et al. "Food allergy in migraine," Lancet 1980; ii: 1-4.

Acupuncture:

L. Lenhard, et al. "Acupuncture in the prophylactic treatment of migraine headache: pilot study," NZ Med J 1983; 96: 663-6.

J. Laiten, "Acupuncture for migraine prophylaxis: a prospective clinical study with six month's follow-up," Am J Chin Med 1975; 3: 271-4.

D. Melchard, et al. "Acupuncture for recurrent headaches: a systematic review of randomized controlled trials," Cephalagia 1999; 19: 779-786.

Homeopathy:

B. Brigo, et al. "Homeopathic treatment of migraines: a randomized double-blind controlled study of sixty cases," Berlin J. Res. Homeopathy 1991; 1 (2): 98.

P. Straumsheim, et al. "Homeopathic treatment of migraine: a double blind, placebo controlled trial of 68 patients," Br. Hom. J. 2000; 89: 4.

H. Walach, et al. "The long-term effects of homeopathic treatment of chronic headaches: one year follow-up and single case time series analysis," Br. Hom. J. 2001; 90:63.

Heart Disease

Co-enzyme Q-10:

T. Ishiyama, et al. "A clinical study of the effect of Coenzyme Q on congestive heart failure," Jpn Heart J 1976; 17: 32.

W. V. Judy, et al. "Myocardial effects of Co-enzyme Q-10 in primary heart failure," Biomedical and Clinical Aspects of Coenzyme Q, (1984; Vol 4 Amsterdam: Elsevier Science Pub: 353-67).

Craetaegus:

V. M. O'Conolly, et al. "Treatment of cardiac performance (NYHA Stages I to II) in advanced age with standardized crataegus extract," Fortschr Med 1986; 104: 805-8.

H. Leuchtgens, "Crataegus special extract WS 1442 in NYHA II heart failure: a placebo controlled randomized double-blind study," Fortschr Med 1993; 111: 352-4.

Homeopathy:

G. Ruiz, et al. "Homeopathic effect on heart rate variability," Br. Hom. J. 1999; 88: 106.

Hepatitis

Glycyrrhizin:

H. Suzuki, et al. "Effects of glycyrrhizin on biochemical tests in patients with chronic hepatitis: double blind trial," Asian Med J 1984; 26: 423-38.

Y. Arase, et al. "The long term efficacy of glycyrrhizin in chronic hepatitis C patients," Cancer 1997; 79: 1494-500.

Silymarin:

E. Magliulo, et al. "Results of a double blind study on the effect of Silymarin in the treatment of acute viral hepatitis, carried out at two medical centres," Med Klin 1978; 73: 1060-5.

R. Schandalik, et al. "Pharmacokinetics of Silybin in bile following administration of Silipide and Silymarin in cholecystectomy patients," Arzneim Forsch 1992; 42: 964-8.

Traditional Chinese Medicine:

R. G. Batey, et al. "Preliminary report of a randomized, double-blind placebo-controlled trial of a Chinese herbal medicine preparation CH-100 in the treatment of chronic hepatitis C" Journal of Gastroenterology and Hepatology 1998; 13: 244-247.

Homeopathy:

J. Bildet, et al. "Etude de l'action de differentes diluitions de phosphorus sur l'hepatite toxique du rat," Ann. Hom. Fr. 1975; 17: (4) 425.

J. Bildet, et al. "Etude au microscope électronique de l'action de diluitions de phosporus 15 CH sur l'hepatite toxique du rat," Homeopathie Francaise 1984; 72: 211.

High Blood Pressure

Potassium:

A. O. Oble, "Placebo controlled trial of potassium supplements in black patients with mild essential hypertension," J Cardiovasc Pharmacol 1989; 14: 294-6.

P. S. Patki, et al. "Efficacy of potassium and magnesium in essential hypertension: a double-blind, placebo-controlled, crossover study," Br J Med 1990; 301: 521-3.

Linolenic acid:

P. Singer, "Alpha- Linolenic Acid vs. long-chain fatty acids in hypertension and hyperlipidemia," Nutr 1992; 8: 133-5.

E. M. Berry, et al. "Does dietary linolenic acid influence blood pressure," Am J Clin Nutr 1986; 44: 336-40.

HIV/AIDS

Traditional Chinese Medicine:

J. H. Burack, et al. "Pilot randomized controlled trial of Chinese herbal treatment for HIV-associated symptoms," Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 1996; 12: 386-393.

Homeopathy:

D. P. Rastogi, et al. "Homeopathy in HIV infection: a trial report of double-blind placebo controlled study," Br. Hom. J. 1999; 88: 49.

Inflammatory Bowel Disease

Sugar consumption:

J. Jarnerot, et al. "Consumption of refined sugar by patients with Crohn's disease, ulcerative colitis, or irritable bowel syndrome," Scand J Gastroenterol 1993; 18: 999-1002.

J. F. Mayberry, et al., "Increased sugar consumption in crohn's disease," Digestion 1980; 20: 323-6.

Folic acid:

L. Elsborg, et al. "Folate deficiency in chronic inflammatory bowel diseases," Scand J Gastroenterol 1979; 14: 1019-24.

L. B. Carruthers, "Chronic diarrhea treated with folic acid," Lancet 1946; I: 849-50.

Insomnia

Melatonin:

A. B. Dollins, et al. "Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance," Proc Natl Acad Sci USA 1994; 91: 1824-8.

C. Mallo, et al. "Effects of a four day nocturnal melatonin treatment on the 24 hour plasma melatonin, cortisol and prolactin profiles in humans," Acta Endocrinologia 1988; 119: 474-97.

Valerian:

P. Leathwood, et al. "Aqueous extract of Valerian root (Valeriana officinalis L.) improves sleep quality in man," Pharmacol Biochem Behavior 1982; 17: 65-71.

O. Lindahl, et al. "Double blind study of a valerian preparation," Pharmacol Biochem Behavior 1989; 32(4): 1065-6.

Irritable Bowel Syndrome

Peppermint oil:

J. M. Hills, et al. "The mechanism of action of peppermint oil in gastrointestinal smooth muscle," Gastroenterol 1991; 101: 55-65.

K. Somerville, et al. "Delayed release peppermint oil capsules (colpermin) for the spastic colon syndrome: a pharmacokinetic study," Br J Clin Pharmacol 1984; 18: 638-40.

Stress management:

E. B. Blanchard, et al. "Relaxation training as a treatment for irritable bowel syndrome," Biofeedback self-regulation 1993; 18: 125-32.

G. Shaw, et al. "Stress management for irritable bowel syndrome: a controlled trail," Digestion 1991; 50: 36-42.

Traditional Chinese Medicine:

Alan Bensoussan, et al. "Treatment of irritable bowel syndrome with Chinese herbal medicine: a randomized controlled trial," Journal of the American Medical Association 1998; 280: 1585-1589.

Kidney Stones

Vitamin C:

J. M Rivers, "Safety of high-level vitamin C ingestion," Int J Vitamin Nutr Res 1989; 30(suppl.): 95-102.

T. R. Wanzilak, et al. "Effect of high dose vitamin C on urinary oxalate levels," J Urol 1994; 151: 834-7.

Macular Degeneration

Zinc:

D. A. Newsome, et al. "Oral zinc in macular degeneration," Arch Ophthalmol 1988; 106: 192-8.

M. Stur, et al. "Oral zinc and the second eye in age-related macular degeneration," Invest Ophthalmol Vis Sci 1996; 37: 1225-35.

Multiple Sclerosis

Food allergy:

D.C. Hewson, "Is there a role for gluten-free diets in multiple sclerosis?" Human Nutr Appl Nutr 1984; 38A: 417-20.

B. A. Agranoff, et al. "Diet and the geographical distribution of multiple sclerosis," Lancet 1974; 2: 1061-6.

Vitamin B-12:

R. Sandyk, et al. "Vitamin B-12 and its relationship to age of onset of multiple sclerosis," Int J Neurosci 1993; 71: 93-9.

C. A. Simpson, et al. "The treatment of multiple sclerosis with massive doses of hydroxocobalamin," Neurology 1965; 15: 599-602.

Nausea and Vomiting

Acupuncture:

A. J. Vickers, "Can acupuncture have specific effects on health? A systematic review of acupuncture antiemesis trials," Journal of the Royal Society of Medicine 1996; 89: 303-311.

E. Ernst, "Acupressure for nausea: a best evidence analysis," European Journal for Physical Medicine and Rehabilitation 1996; 6: 29-30.

Nausea of Vomiting of Pregnancy

Vitamin B-6:

V. Sahakian, et al. "Vitamin B-6 is effective for nausea and vomiting of pregnancy: a randomized, double-blind placebo-controlled study," Obstet Gynecol 1991; 78: 33-6.

T. Vutyananich, et al. "Pyridoxine for nausea and vomiting in pregnancy: a randomized, double-blind, placebo-controlled trial," Am J Obstet Gynecol 1995; 173: 881-4.

Ginger:

D. Mowrey, et al. "Motion sickness, ginger, and psychophysics," Lancet 1982; 1: 655-7.

W. Fischer-Rasmussen, et al. "Ginger treatment of hyperemesis gravidarum," Eur J Obstet Gynecol Reprod Biol 1990; 38: 19-24.

Osteoarthritis

Glucosamine sulfate:

J. M. Pujalte, et al. "Double-blind clinical evaluation of oral glucosamine sulphate in the basic treatment of osteoarthrosis," Curr Med Res Opin 1980; 7: 110-4.

A. Drovanti, et al. "Therapeutic activity of the oral glucosamine sulfate in osteoarthrosis: a placebo-controlled double-blind investigation," Clin Ther 1980; 3: 260-72.

Pantothenic acid:

J.C. Anand, "Osteoarthritis and pantothenic acid," Lancet 1963; 2: 1168.

Osteoporosis

Exercise:

S. B. Jaglar, et al. "Past and recent physical activity and the risk of osteoporosis," Am J Epidemiol 1993; 138: 107-118.

J. C. Opriot, et al. "Physical activity as therapy for osteoporosis," Can Med Assoc J 1996; 155: 940-44.

Diet:

J. Thorn, et al. "The influence of refined carbohydrate on urinary calcium excretion," Br J Urol 1978; 50: 459-64.

G. Wyshak, et al. "Carbonated beverages, dietary calcium, the dietary calcium/phosphorus ratio, and bone fractures in girls and boys," J Adolesc Health 1994; 15: 210-15.

Pain

Acupuncture:

M. Patel, et al. "A meta-analysis of acupuncture for chronic pain," International Journal of Epidemiology 1989; 18: 900-906.

M. W. van Tulde, et al. "The effectiveness of acupuncture in the treatment of low back pain," Spine 1999; 24: 1113-1123.

A. R. White, et al. "A systematic review of randomized controlled trials of acupuncture for neck pain," Rheumatology 1999; 38: 143-147.

Homeopathy:

C. Stam, et al. "The efficacy and safety of a homeopathic gel in the treatment of acute low back pain: A multi-centre, randomised, double-blind comparative clinical trial," Br. Hom. J. 2001; 90: 21.

Periodontal Disease

Acupuncture:

O. Alvares, et al. "The effect of subclinical ascorbate deficiency on periodontal disease in nonhuman primates," J Periodontal Res 1984; 16: 628-36.

M. Alfano, et al. "Effect of ascorbic acid deficiency on the permeability and collagen biosynthesis of oral mucosal epithelium," Ann NY Acad Sci 1975; 258: 253-63.

Folic acid:

A. Pack, et al. "Effects of topical and systemic folic acid supplementation on gingivitis in pregnancy," J Clin Periodontal 1980; 7: 402-4.

A. Pack, et al. "Effects of extended systemic and topical folate supplementation on gingivitis of pregnancy," J Clin Periodontal 1982; 9: 275-80.

Post-operative Healing

Homeopathy:

G. Aulagnier, "Action d'un traitement homéopathique sur la reprise du transit post opératoire," Homéopathie 1985; 6: 42.

O. Hart, et al. "Double-blind, placebo-controlled, randomized clinical trial of homeopathic Arnica C30 for pain and infection after total abdominal hysterectomy," J. R. Soc. Med. 1997; 90: 73.

M. J. Mayaux, et al. "Controlled clinical trial of homeopathy in postoperative ileus," Lancet 1988; 1: 528.

Premenstrual Syndrome

Magnesium:

F. Facchinetti, et al. "Oral magnesium successfully relieves premenstrual mood changes," Obstet Gynecol 1991; 78: 177-81.

D. L. Rosenstein, et al. "Magnesium measures across the menstrual cycle in premenstrual syndrome," Biol Psychiatr 1994; 35: 557-61.

Copper, Zinc:

C. J. Chuong, et al. "Zinc and copper levels in premenstrual syndrome," Fertility Sterility 1994; 62: 313-20.

C. Posacki, et al. "Plasma, copper, zinc and magnesium levels in patients with premenstrual tension syndrome," Acta Obstet Gynecol Scand 1994; 73: 452-5.

Prostate Enlargement:

Zinc:

A. Leake, et al. "The effect of zinc on the 5 alpha-reduction of testosterone by the hyperplastic human prostate gland," J Steroid Biochem 1984; 20: 651-5.

A. M. Judd, et al. "Zinc acutely, selectively and reversibly inhibits pituitary prolactin secretion," Brain Res 1984; 294: 190-2.

Serenoa repens:

S. Boccafoschi, et al. "Comparison of Serenoa repens extract with placebo by controlled clinical trial in patients with prostate adenomatosis," Urologia 1983; 50: 1257-68.

G. Champlault, et al. "A double-blind trial of an extract of the plant Serenoa repens in benign prostatic hyperplasia," Br J Clin Pharmacol 1984; 18: 461-2.

Psoriasis

Sarsaparilla:

F. M. Thurmon, "The treatment of psoriasis with sarsaparilla compound," NEJM 1942; 227: 128-33.

Omega-3 fatty acids:

F. Grimmunger, et al. "A double-blind, randomized, placebo-controlled trial of n-3 fatty acid based lipid infusion in acute, extended guttate psoriasis," Clin Invest 1993; 71: 634-43.

P. D. I. Maurice, et al. "The effects of dietary supplementation with fish oil in patients with psoriasis," Br J Dermatol 1987; 1117: 599-606.

Capsaicin:

C.N. Ellis, et al. "A double-blind evaluation of topical capsaicin in pruritic psoriasis," J Am Acad Dermatol 1993; 29: 438-42.

J. E. Bernstein, et al. "Effects of topically applied capsaicin on moderate and severe psoriasis vulgaris," J Am Acad Dermatol 1986; 15: 504-7.

Rheumatoid Arthritis

Food allergy:

L. G. Darlington, et al. "Placebo-controlled, double-blind study of dietary manipulation therapy in rheumatoid arthritis," Lancet 1986; 1: 236-8.

M. A. F. J. Van de Laar, et al. "Food intolerance in rheumatoid arthritis I: a double-blind, controlled trial of the clinical effects of elimination of milk allergens and azo dyes," Annals Rheum Dis 1992; 51: 298-302.

Evening primrose oil:

J. Jantti, et al. "Evening primrose oil in rheumatoid arthritis: changes in serum lipids and fatty acids," Ann Rheum Dis 1989; 48: 124-7.

M. Brzeski, et al. "Evening primrose oil in patients with rheumatoid arthritis and side effects of non-steroidal anti-inflammatory drugs," Br J Rheumatol 1991; 30: 371-2.

Homeopathy:

R. G. Gibson, et al. "Homeopathic therapy in rheumatoid arthritis: evaluation by double-blind clinical therapeutic trial," Brit. J. Clin. Pharmac. 1980; 9: 453.

Sterility

Vitamin C:

E. Dawson, et al. "Effect of vitamin C supplementation on sperm quality of heavy smokers," FASEB J 1991; 5: A915.

E. B. Dawson, et al. "Effect of ascorbic acid on male fertility," Ann NY Acad Sci 1987; 498: 312-23.

Panax ginseng:

M. Yamamoto, et al. "Endocrinological and metabolic actions of P. ginseng principles," Proceedings 3rd International Ginseng Symposium 1980: 115-9.

W.S. Fahim, et al. "Effect of panax ginseng on testosterone level and prostate in male rats," Arch Androl 1982; 8: 261-3.

Stroke

Acupuncture:

E. Ernst, "Acupuncture as an adjuvant therapy in stroke rehabilitation?" Wiener Medizinische Wochenschrift 1996; 146: 556-558.

B. Jahanson, et al. "Can sensory stimulation improve the functional outcome in stroke patients?" Neurology 1993; 43: 2189-2195.

Homeopathy:

R. H. Savage, et al. "A double blind trial to assess the benefit of Arnica montana in acute stroke illness," Brit. Hom. J. 1977; 66: 207.

R. H. Savage, et al. "A further double blind trial to assess the benefit of Arnica montana in acute stroke illness," Brit. Hom. J. 1978; 67: 210.

TMJ

Acupuncture:

E. Ernst, et al. "Acupuncture as a treatment for temporomandibular joint dysfunction: a systematic review of randomized trials," Archives of Otolaryngology, Head, and Neck Surgery 1999; 125: 269-272.

Toothache

Acupuncture:

E. Ernst, et al. "The effectiveness of acupuncture in treating acute dental pain: a systematic review," British Dental Journal 1998; 184: 443-447.

Ulcers

Pectin:

J. Y. Kang, et al. "Dietary supplementation with pectin in the maintenance treatment of duodenal ulcer," Scand J Gastroenterol 1988; 23: 95-9.

G. Cheney, "Rapid healing of peptic ulcers in patients receiving fresh cabbage juice," Cal Med 1949; 70: 10-14.

Deglycyrrhizinated licorice:

J. Marle, et al. "Deglycyrrhizinised liquorice (DGL) and the renewal of rat stomach epithelium," Eur J Pharm 1981; 72: 219.

A. G. Turpie, et al. "Clinical trial of deglycyrrhizinated liquorice in gastric ulcer," Gut 1969; 10: 299-303.

Varicose Veins

Centella asiatica:

C. Allegra, "Comparative capillaroscopic study of certain bioflavonoids and total triterpenic fractions of Centella asiatica in venous insufficiency," Clin Terap 1984; 110: 550.

J. P. Pointel, et al. "Titrated extract of Centella asiatica (teca) in the treatment of venous insufficiency of the lower limbs," Angiology 1987; 38: 46-50.

Chestnut:

C. Diehm, et al. "Comparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiency," Lancet 1996; 347: 292-4.

G. Hitzenberger, "The therapeutic effectiveness of chestnut extract," Wien Med Wochenschr 1989; 139(17): 385-9.

Vertigo

Homeopathy:

M. Weiser, et al. "Homeopathic vs conventional treatment of vertigo: a randomized double-blind controlled clinical study," Arch. Otolaryngol. Head Neck Sur. 1998; 124: 879.

Warts

Homeopathy:

J. T. Kainz, et al. "Homeopathic versus placebo therapy of children with warts on the hands: a randomized, double-blind clinical trial," Dermatology 1996; 4: 318.

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© 2004, 2006, 2012 Colleen Huber unless otherwise noted.
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